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Professor Chien-Chih Yang

Professor Chien-Chih Yang and Chairman

Chien-Chih Yang

Title Professor
Education Ph.D., Department of Biochemistry, University of Cambridge
Research Expertise Biochemistry, Protein Chemistry
LAB Biochemistry Lab. (AC2-510)
TEL +886-2-3366-4445
Personal webpage The GREEN Lab


Using   Genomic and proteomic tools to probe the

            Regulatory mechanism of plants in response to

            Environmental stresses: From

            Evolution to

            Next GREEN revolution


  1. Chen Hsu , Hsin-Ya Tsai, Chi-Fon Chang , Chien-Chih Yang, Nan-Wei Su (2022, Aug). Discovery of a novel phosphotransferase from Bacillus subtilis that phosphorylates a broad spectrum of flavonoids. Food Chem.,
  2. Liao HS, Yang CC, Hsieh MH. Nitrogen deficiency- and sucrose-induced anthocyanin biosynthesis is modulated by HISTONE DEACETYLASE15 in Arabidopsis. J Exp Bot 2022.(SCI)
  3. Chen EH, Weng CW, Li YM, Wu MC, Yang CC, Lee KT, Chen RP, Cheng CP. De Novo Design of Antimicrobial Peptides With a Special Charge Pattern and Their Application in Combating Plant Pathogens. Front Plant Sci 2021; 12: 753217.(SCI)
  4. Wang YJ, Lee SC, Hsu CH, Kuo YH, Yang CC, Lin FJ. Antcins, triterpenoids from Antrodia cinnamomea, as new agonists for peroxisome proliferator-activated receptor alpha. J Food Drug Anal 2019; 27(1): 295-304.(SCI)
  5. Shen HC, Chen YH, Lin YS, Chu BK, Liang CS, Yang CC, Chen RP. Segments in the Amyloid Core that Distinguish Hamster from Mouse Prion Fibrils. Neurochem Res 2019; 44(6): 1399-409.(SCI)
  6. Huang YC, Hsiang EC, Yang CC, Wang AY. New insight into the catalytic properties of rice sucrose synthase. Plant Mol Biol 2015; 90(1-2):127-35.(SCI)
  7. Liang CH, Yang CC. Identification of ICE1 as a negative regulator of ABA-dependent pathways in seeds and seedlings of Arabidopsis. Plant Mol Biol 2015; 88(4-5): 459-70.(SCI)
  8. Hsieh YL, Lu CF, Chiang BY, Liao SC, Chen RY, Lin CS, Wang AY, Yang CC. Molecular Characterization of Ethylene Response Sensor 1 (BoERS1) in Bambusa oldhamiiPlant Mol Biol Rep 2015: 1-12.(SCI)
  9. Yeh SH, Lee BH, Liao SC, Tsai MH, Tseng YH, Chang HC, Yang CC, Jan HC, Chiu YC, Wang AY. Identification of genes differentially expressed during the growth ofBambusa oldhamiiPlant Physiol Biochem 2013; 63: 217-26.(SCI)
  10. Chia JC, Yang CC, Sui YT, Lin SY, Juang RH. Tentative identification of the second substrate binding site in Arabidopsis phytochelatin synthase. PLoS ONE 2013; 8(12): e82675.(SCI)
  11. Kao AL, Lin YH, Chen RP, Huang YY, Chen CC, Yang CC. E3-independent ubiquitination of AtMAPR/MSBP1. Phytochemistry. 2012; 78: 7-19. (SCI)
  12. Hsieh LS, Hsieh YL, Yeh CS, Cheng CY, Yang CC, Lee PD. Molecular characterization of a phenylalanine ammonia-lyase gene (BoPAL1) from Bambusa oldhamii. Mol Biol Rep. 2011; 38(1): 283-90. (SCI)
  13. Chang JC, Liao YC, Yang CC, Wang AY. The purine-rich DNA binding protein OsPuralpha participates in the regulation of the rice sucrose synthase 1 gene expression.Physiol Plant. 2011. (SCI)
  14. Hsieh LS, Yeh CS, Pan HC, Cheng CY, Yang CC, Lee PD. Cloning and expression of a phenylalanine ammonia-lyase gene (BoPAL2) from Bambusa oldhamii in Escherichia coli and Pichia pastoris. Protein Expr Purif. 2010; 71(2): 224-30. (SCI)
  15. Hsieh LS, Ma GJ, Yang CC, Lee PD. Cloning, expression, site-directed mutagenesis and immunolocalization of phenylalanine ammonia-lyase in Bambusa oldhamii.Phytochemistry. 2010; 71(17-18): 1999-2009. (SCI)
  16. Chen CY, Hsieh MH, Yang CC, Lin CS, Wang AY. Analysis of the cellulose synthase genes associated with primary cell wall synthesis in Bambusa oldhamii.Phytochemistry. 2010; 71(11-12): 1270-9. (SCI)
  17. Chen CC, Liang CS, Kao AL, Yang CC. HHP1, a novel signalling component in the cross-talk between the cold and osmotic signalling pathways in Arabidopsis. J Exp Bot. 2010; 61(12): 3305-20. (SCI)
  18. Wang HC, Wu JS, Chia JC, Yang CC, Wu YJ, Juang RH. Phytochelatin synthase is regulated by protein phosphorylation at a threonine residue near its catalytic site. J Agric Food Chem. 2009; 57(16): 7348-55. (SCI)
  19. Ho CC, Lee LY, Huang KT, Lin CC, Ku MY, Yang CC, Chan SI, Hsu RL, Chen RP. Tuning the conformational properties of the prion peptide. Proteins. 2009; 76(1): 213-25. (SCI)
  20. Chen TH, Huang YC, Yang CS, Yang CC, Wang AY, Sung HY. Insights into the catalytic properties of bamboo vacuolar invertase through mutational analysis of active site residues. Phytochemistry. 2009; 70(1): 25-31. (SCI)
  21. Chen CC, Liang CS, Kao AL, Yang CC. HHP1 is involved in osmotic stress sensitivity in Arabidopsis. J Exp Bot. 2009; 60(6): 1589-604. (SCI)
  22. Kao AL, Chang TY, Chang SH, Su JC, Yang CC. Characterization of a novel Arabidopsis protein family AtMAPR homologous to 25-Dx/IZAg/Hpr6.6 proteins. Bot Bul Acad Sin. 2005; 46(2): 107-18. (SCI)
  23. Lai CP, Lee CL, Chen PH, Wu SH, Yang CC, Shaw JF. Molecular analyses of the Arabidopsis TUBBY-like protein gene family. Plant Physiol. 2004; 134(4): 1586-97. (SCI)
  24. Hsu JH, Yang CC, Su JC, Lee PD. Purification and characterization of a cytosolic starch phosphorylase from etiolated rice seedlings. Bot Bul Acad Sin. 2004; 45(3): 187-96. (SCI)
  25. Chen PY, Gopalacushina BG, Yang CC, Chan SI, Evans PA. The role of a beta-bulge in the folding of the beta-hairpin structure in ubiquitin. Protein Sci. 2001; 10(10): 2063-74. (SCI)
  26. Yang CC, Packman LC, Scrutton NS. The primary structure of Hyphomicrobium X dimethylamine dehydrogenase. Relationship to trimethylamine dehydrogenase and implications for substrate recognition. Eur J Biochem. 1995; 232(1): 264-71. (SCI)
  27. Raine AR, Yang CC, Packman LC, White SA, Mathews FS, Scrutton NS. Protein recognition of ammonium cations using side-chain aromatics: a structural variation for secondary ammonium ligands. Protein Sci. 1995; 4(12): 2625-8. (SCI)