ntubst2019EN

Highlight I Liposomes in Flow Injection Systems

1. Application of Liposomal Bioluminescent Label in the Development of Flow Injection ImmunoAnalytical System [Anal. Chem. 2005, 77 (11), 3431–3436]; illustrated in Figure 2
2. Application of Ganglioside‐Sensitized Liposomes in a Flow Injection Immunoanalytical System for the Determination of Cholera Toxin [Anal. Chem. 2007, 79 (1), 246–250].

 

 

圖二 (A) Schematic representation of a Flow‐Injection Liposome Immunoanalytical (FILIA) system with bioluminescence detection. (B) Reproducibility of the bioluminescence signal.

 

Highlight II Development of Electrochemial Immunosensors

1. Electrochemical Immunosensor for Cholera Toxin Using Liposomes and poly(3,4‐ ethylenedioxythiophene)‐Coated Carbon Nanotubes [Anal. Chem. 2006, 78 (4), 1115–1121]; illustrated in Figure 3.
2. Dual Electrochemical Determination of Glucose and Insulin Using Enzyme and Ferrocene Microcapsules [Biosens. Bioelectron. 2007, 22, 1147–1153]; illustrated in Figure 4.

 

 

 

 

圖三 (A) Schematic representation of an electrochemical immunosensor for cholera toxin. (B) Calibration plot for cholera toxin. Inset: Linear portion of the main curve.

 

圖四 Schematic representation of the encapsulation, biolabeling, and detection of glucose and insulin.

 

Highlight III Liposomes in Immunoaffinity Chromatographic Biosensors

1. Using Liposomal Fluorescent Biolabels To Develop an Immunoaffinity Chromatographic Biosensing System for Biotin [Anal. Chem. 2008, 80 (16), 6405–6409]; illustrated in Figure 5.

圖五 Schematic representation of the operation of an immunosensor for the detection of biotin.

1. Chuang, M.-C., Lai, H.-Y., Ho, J.-a. A.*, Chen, Y.-Y. (2013) Multifunctional microelectrode array (mMEA) chip for neural-electrical and neural-chemical interfaces: Characterization of comb interdigitated electrode towards dopamine detection. Biosensors and Bioelectronics, 41, 602–607. DOI: 10.1016/j.bios.2012.09.030
2. Tien, C.-Y., Jou, A.F.-J., Fan, N.-C., Chuang, M.-C., Ho, J.-A.A.* (2013) Preparation of Liposomal Progesterone and Its Application on the Measurement of Progesterone Interpreted via Electrochemical and Colorimetric Sensing Platforms. Electroanalysis, 25(4), 1017–1022. DOI: 10.1002/elan.201200563
3. Teng, I.-T., Chang, Y.-J., Wang, L.-S., Lu, H.-Y., Wu, L.-C., Yang, C.-M., Chiu, C.-C., Yang, C.-H., Hsu, S.-L., Ho, J.-a. A.* (2013) Phospholipid-functionalized mesoporous silica nanocarriers forselective photodynamic therapy of cancer. Biomaterials, 34, 7462-7470. DOI: 10.1016/j.biomaterials.2013.06.001
    
4. Tanwar, S.,* Ho, J.-a. A., Magi, E. (2013) Green synthesis and characterization of novel gold nanocomposites for electrochemical sensing applications. Talanta, 117, 352-358. DOI:10.1016/j.talanta.2013.09.011
5. Liao, W.-C., Chuang, M.-C., Ho, J.-a. A.* (2013) Electrochemical sensor for multiplex screening of genetically modified DNA: Identification of biotech crops by logic-based biomolecular analysis. Biosensors and Bioelectronics, 50, 414-420. DOI: 10.1016/j.bios.2013.06.044

2012

1. Ho, J.-a. A.*, Jou, A. F.J., Wu, L.C., Hsu, S.L. (2012) Development of an immunopredictor for the evaluation of the risk of cardiovascular diseases based on the level of soluble P-selectin. Methods, 56(2), 223-229. (SCI) DOI: 10.1016/j.ymeth.2011.10.014 
2. Prasad, K. S., Chuang, M.C.,  Ho J.-a. A.* (2011) Synthesis, characterization, and electrochemical applications of carbon nanoparticles derived from castor oil soot. Talanta, 88(15), 445-449. (SCI) DOI:10.1016/j.talanta.2011.10.056 
3. Ho, J.-a. A.*, Kuo, T.Y., Yu, W.G. (2012) Dual polarization interferometric and capillary electrophoretic analysis of supported lipid bilayer constructed on silica-based surface: Evaluation of its anti-protein adsorption effect. Analytica Chimica Acta, 714(10), 127-133. DOI: 10.1016/j.aca.2011.11.062
4. Ho, J.-a. A.*, Chang, H.C., Su, W.T. (2012) DOPA-mediated reduction allows the facile synthesis of fluorescent gold nanoclusters for use as sensing probes for ferric Ions. Analytical Chemistry, 82(7), 3246-3253. (SCI) DOI: 10.1021/ac203362g
5. Chuang, M.C. and Ho, J.-a. A.* (2012) Efficient electrocatalytic oxidation of water: minimization of catalyst loading by an electrostatic assembly of hydrous iridium oxide colloids. RSC Advances, 2, 4092-4096. (SCI) DOI: 10.1039/C2RA00895E
6. Tanwar, S. Chuang, M.C., Prasad, K.S., Ho, J.-a. A.* (2012) Template-free Synthesis of Electroactive Au-Calix-PPY nanocomposite for Electrochemical Sensor Applications. Green Chemistry, 14, 799-808. (SCI) DOI: 10.1039/C2GC16232F
7. Prasad, K.S., Fan, N.C., Wi, L.C., Chang, J.C., Wang, L.S., Hwang, K.C., Hwu, J.R., Horng, J.C., Lin, C.C., Ho, J.-a. A.* (2012) A Tunable Multicolor Photoluminescent Nanocarbon Prepared from Castor Oil Soot.  Journal of the Chinese Chemical Society, 59(6), 802–808. (SCI) DOI: 10.1002/jccs.201100626
8. Fan, N. C., Cheng, F. Y., Ho, J. A.*, Yeh, C. S.* (2012) Photocontrolled Targeted Drug Delivery: Photocaged Biologically Active Folic Acid as a Light-Responsive Tumor-Targeting Molecule. Angew. Chem. Int. Ed., 51(35), 8806-8810. (SCI) DOI: 10.1002/anie.201203339
9. Ho, J.-a. A.*, Fan, N.C., Jou, A. F.J., Wu, L.C., Sun, T.P., (2012) Monitoring the subcellular localization of doxorubicin in CHO-K1 using MEKC−LIF: Liposomal carrier for enhanced drug delivery. Talanta, 99(15), 683-688. (SCI) DOI: 10.1016/j.talanta.2012.06.077
10. Freeman, R., Girsh, J., Jou, A. F.J., Ho, J.-a. A., Hug, T., Dernedde, J., Willner, I.*, (2012) Optical Aptasensors for the Analysis of the Vascular Endothelial Growth Factor (VEGF). Anal. Chem., 84(14), 6192–6198.(SCI) DOI: 10.1021/ac3011473
11. Viswanathana, S.*, Ranib, C., Ho, J.-a. A, (2012) Electrochemical immunosensor for multiplexed detection of food-borne pathogens using nanocrystal bioconjugates and MWCNT screen-printed electrode. Talanta, 94(30), 315–319. (SCI) DOI: 10.1016/j.talanta.2012.03.049
12. Wang, L.S., Chuang, M.C., Ho, J.-a. A.* (2012) Nanotheranostics – a review of recent publications. Int. J. Nanomedicine, 7, 4679-4695. (SCI) DOI: 10.2147/IJN.S33065

2011

1. Su, L.C., Chang, Y.F., Chou, C., Ho, J.-a. A., Li, Y.C., Chou, L.D., Lee, C.C. (2011). Binding kinetics of biomolecule interaction at ultralow concentrations based on gold nanoparticle enhancement. Analytical Chemistry, 83(9): 3290-6. (SCI) DOI: 10.1021/ac1028616
2. Jeng, C.C., Cheng, S.H., Ho, J.-a. A., Huang, S. H.-Y., Chang, J. C., Tsai, P.J., Yang, C.S., Lo, L.W. (2011) Dynamic probing of nanoparticle stability in vivo: a liposomal model assessed using in situ microdialysis and optical imaging. Journal of Nanomaterials, v.2011, 932719. (SCI) DOI:10.1155/2011/932719
    

2010

2009

1. Ho, J.-a. A.*; Lin, Y.C.; Wang, L.S.; Hwang, K.C. and Chou, P.T. (2009). Carbon nanoparticle‐enhanced immunoelectrochemical detection for protein tumor marker with CdS biotracers. Analytical Chemistry, 81(4), 1340-1346. (SCI) DOI: 10.1021/ac801832h
2. Liao, W. C., Ho, J.-a. A.* (2009). Attomole DNA electrochemical sensor for the detection of Escherichia coli O157. Analytical Chemistry, 81(7), 2470-2476. (SCI) DOI: 10.1021/ac8020517
3. Ho, J.-a A.*, Chiu, J.K., Hsu, W.L., Hong, J.C., Lin, C.C., Hwang, K.C. and Hwu, J.R. (2009). Gold-Nanostructured Immunosensor for the Electrochemical Sensing of Biotin Based on Liposomal Competitive Assay. Journal of Nanoscience and Nanotechnology, 9(4), 2324-2329. (SCI) DOI: 10.1166/jnn.2009.SE40
4. Viswanathan, S., Rani, C., Vijay Anand, A., Ho, J.-a. A. (2009). Disposable electrochemical immunosensor for carcinoembryonic antigen using ferrocene liposomes and MWCNT screen-printed electrode. Biosensors and Bioelectronics, 24(7), 1984-1989. (SCI) DOI: 10.1016/j.bios.2008.10.006
5. Wu, L.C.*; Chang, L.H.; Chen, S.H.; Fan, N.C.; Ho, J.-a. A.** (2009). Antioxidant activity and melanogenesis inhibitory effect of the acetonic extract of Osmanthus fragrans: A potential natural and functional food flavor additive. LWT - Food Science and Technology, 42(9), 1513-1519. (SCI) DOI:10.1016/j.lwt.2009.04.004
6. Chien, H.T., Lee, C.K., Chiu, H.K., Hsu, K.C., Chen, C.C.,* Ho, J.‐a. A., Chou, C. (2009). The Comparison between the Graded Photonic Crystal Coupler and Various Coupler. Journal of Lightwave Technology, 27(14), 2570-2574. (SCI) DOI: 10.1109/JLT.2008.2012271
7. Ho, J.-a. A.*, Hung, C.H.,Wu, L.C., Liao, M.Y. (2009). Folic acid-anchored PEGgylated phospholipid bioconjugate and its application in a liposomal immunodiagnostic assay for folic acid. Analytical Chemistry, 81(14), 5671-5677. (SCI) DOI: 10.1021/ac900402v
8. Lin, P.C., Adak, A.K., Ueng. S.H., Huang, L.D., Huang, K.T., Ho, J.-a.A., Lin C.C. (2009) DAST-mediated regioselective anomeric group migration in sacchardies. Journal of Organic Chemistry, 74(11), 4041-4048. (SCI) DOI: 10.1021/jo900516r
9. Hwu, J.R.*, Huang,  J.-T. J., Tsai, F.Y., Tsay, S.C., Hsu, M.H., Hwang, K.C., Horng, J.C., Ho, J.-a. A, Lin, C.C. (2009). Photochemical Activities of N-Nitroso Carboxamides and Sulfoximides and Their Application to DNA Cleavage, Chemistry - A European Journal, 15(35), 8742 - 8750 (SCI) DOI: 10.1002/chem.200802571

2008

1. Ho, J-a A.*, Zeng, S.C., Tseng, W.H., Lin, Y.J. and Chen, C.H. (2008). Liposome-Based Immunostrip for the Rapid Detection of Salmonella. Analytical and Bioanalytical Chemistry, 391(2), 479-485. (SCI) DOI: 10.1007/s00216-008-1875-5

2. Hsin,Y.L., Lin, C.F., Liang, Y.C., Hwang, K.C., Horng, J.C., Ho, J-a A., Lin, C.C. and Hwu, J.R.(2008). Microwave Arcing Induced Formation and Growth Mechanisms of Core/Shell Metal/Carbon Nanoparticles in Organic Solutions. Advanced Functional Materials, 18(14), 2048-2056. (SCI) DOI: 10.1002/adfm.200701407

3. Ho, J.-a A.* and Hung, C.H. (2008). Using Liposomal Fluorescent Biolabels To Develop an Immunoaffinity Chromatographic Biosensing System for Biotin. Analytical Chemistry, 80(16), 6405-6409. (SCI) DOI: 10.1021/ac800850w

2007

1. Wu, L.C. and Ho, J-a A. In Spirulina in Human Nutrition and Health, Gershwin, M.E. and Belay, A. (Eds) (2007). Chap 6 (p119-152), CRC Press, Boca Raton, FL, USA. (Book Chapter)

2. Subramanian, V., Liao, W.C., Huang, C.C., Hsu, W.L. and Ho, J-a A.* (2007). Rapid Analysis of L-dopa in Urine Samples Using Gold Nanoelectrode Ensembles. Talanta, 74, 229-234. (SCI) DOI: 10.1016/j.talanta.2007.05.056

3. Kim, B.Y., Swearingen, C.B., Ho, J-a A., Romanova, E.V., Bohn, P.W. and Sweedler, J.V. (2007). Direct Immobilization of Fab’ in Nanocapillaries for Manipulating Mass-Limited Samples. Journal of American Chemical Society, 129(24), 7620-7626. (SCI) DOI: 10.1021/ja070041w

4. Ho, J-a A.*, Wu, L.C., Huang, M.R., Lin, Y.J., Baeumner, A.J. and Durst, R.A. (2007). Application of Ganglioside-sensitized Liposomes in a Flow-Injection Immunoanalytical System for the Determination of Cholera Toxin. Analytical Chemistry, 79(1), 246-250. (SCI) DOI: 10.1021/ac060889n

5. Subramanian, V. and Ho, J-a A.* (2007). Dual Electrochemical Determination of Glucose and Insulin Using Enzyme and Ferrocene Microcapsules. Biosensors and Bioelectronics, 22(6), 1147-1153. (SCI) DOI: 10.1016/j.bios.2006.07.031

6. Ho, J-a A.*, Wu, L.C, Fan, N.C., Lee, M.S., Kuo, H.Y. and Yang, C.S. (2007). Development of a Long-life Capillary Enzyme Bioreactor for the Determination of Blood Glucose. Talanta, 71, 391-396. (SCI) DOI: 10.1016/j.talanta.2006.04.023

2006

1. Subramanian, V., Wu, L.C., Huang, M.R. and Ho, J-a A.* (2006). Electrochemical Immunosensor for Cholera Toxin Using Liposomes and poly(3,4-ethylenedioxythiophene)- Coated Carbon Nanotubes. Analytical Chemistry, 78(4), 1115-1121. (SCI) DOI: 10.1021/ac051435d

2. Ho, J-a A.*, Zeng, S.C., Huang, M.R. and Kuo, H.Y. (2006). Development of Liposomal Immunosensor for the Measurement of Insulin with Femtomole Detection. Analytica Chimica Acta, 556, 127-132. (SCI) DOI: 10.1016/j.aca.2005.08.074

3. Wu, L.C.*, Hsu, H.W., Chen, Y.C., Chiu, C.C., Chang, C.W., Lin, Y.Y. and Ho, J-a A.* (2006). Antioxidant and Antiproliferative Activities of Red Pitaya. Food Chemistry, 95, 319-327. (SCI) DOI: 10.1016/j.foodchem.2005.01.002

4. Ho, J-a A.*, Kuo, H.Y., Wang, Y.T. and Yang, C.S. (2006). Occurrence of Aristolochic Acids in Over-the-Counter Chinese Prepared Medicines. Asian Journal of Chemistry, 18(1)253-258. (SCI)

2005

1. Ho, J-a A.* and Huang, M.R. (2005). Application of Liposomal Bioluminescent Label in the Development of Flow Injection Immunoanalytical System. Analytical Chemistry, 77(11), 3431-3436. (SCI) DOI: 10.1021/ac0484474

2. Wu, L.C., Ho, J-a A., Shieh, M.C. and Lu, I.W. (2005). Antioxidant and Antiproliferative Activities of Spirulina and Chlorella Water Extracts. Journal of Agricultural and Food Chemistry, 53(10), 4207-4212. (SCI) DOI: 10.1021/jf0479517

2004

1. Lo, L.W., Ho, J-a A, Chang, Y.H., Chang, C.H, Yang, C.S. (2004). Potential Usage of Liposome-encapulated Phosphor for in vivo Imaging of Tissue Oxygenation. Biomedical Engineering Applications, Basis and Communications. 16(4), 224-229. (EI)
2. Ho, J-a A.,* Hsu, H.W. and Huang, M.R. (2004). Liposome-based Microcapillary Immunosensor for Detection of Escherichia coli O157:H7. Analytical Biochemistry. 330:342-349. (SCI) DOI: 10.1016/j.ab.2004.03.038

2003

1. Ho, J-a A.* and Hsu, H.W. (2003). Procedures for Preparing Escherichia coli O157:H7 Immunoliposome and Its Application in Liposome Immunoassay. Analytical Chemistry. 75:4330-4334. (SCI) DOI: 10.1021/ac0343580

2. Wu, L.C., Chen, Y.C., Ho, J-a A. and Yang, C.S. (2003). Inhibitory Effect of Red Koji Extracts on Mushroom Tyrosinase. Journal of Agricultural and Food Chemistry. 51: 4240-4246. (SCI) DOI: 10.1021/jf034064f
3. Ho, J-a A.* and Durst, R.A. (2003). Detection of Fumonisin B1: Comparison of Flow-injection Liposome Immunoanalysis with High-performance Liquid Chromatography. Analytical Biochemistry. 312:7-13. (SCI) DOI: 10.1016/S0003-2697(02)00393-7

2001-2002

1. Ho, J-a A.* and Wauchope, R.D. (2002). A rapid strip liposome immunoassay for aflatoxin B1. Analytical Chemistry. 74:1493-1496. (SCI) DOI: 10.1021/ac010903q
2. Ho, J-a A., Yang, C.S. and Tzeng, H.F. (2001). Overview of capillary electrochromatography. 化學. 59(3):399-408.
3. Ho, J-a A.* and Durst, R.A. (2000). Preparation of reagents for the determination of fumonisin B1 by flow-injection immunoanalyis. Analytica Chimica Acta. 414:51-60. (SCI) DOI: 10.1016/S0003-2670(00)00782-0
4. Ho, J-a A.* and Durst, R.A. (2000). Development of a flow-injection liposome immunoanalytical (FILIA) system for fumonisin B1. Analytica Chimica Acta. 414:61-69. (SCI) DOI: 10.1016/S0003-2670(00)00786-8